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TRIPRESS is indicated in the treatment of depressive illness especially where sleep disturbance anxiety or agitation is a presenting symptom. Sleep disturbance is controlled within 24 hours and true antidepressant action follows within 7-10 days.Dosage and AdministrationAdultsMild/Moderate Depression in General PracticeThe recommended dosage is 50-75mg orally given two hours before bedtime the larger dose (75mg) being preferable for those patients with more marked sleep disturbance. Treatment should be continued for at least three weeks.Moderate/Severe Depression (Patients under Psychiatric Supervision)Initial dosage - 75mg orally per day. This is best given as a single dose late in the evening or as 25mg midday and 50mg late in the evening. Dosage should then be increased as necessary until the optimal therapeutic level is reached usually 150-300mg per day. Treatment at this dosage should be continued for four to six weeks dosage then being reduced to a maintenance level usually within the range of 75-150mg per day for two to three months. Giving most of the total daily dosage at night induces a rapid return to normal sleep reduces the need for night-time sedation and minimises daytime drowsiness.ElderlyInitially 10-25mg three times a day. The initial dose should be increased with caution under close supervision.Half the normal maintenance dose may be sufficient to produce a satisfactory clinical response.Adolescent DepressionNot recommended for use in adolescent patients 13-18 years of age for the treatment of depression unless under the supervision of a specialist.Impaired Liver FunctionAs trimipramine is metabolised in the liver patients with liver disease may require a reduced dosage.Renal FailureTrimipramine should be used with caution in patients with chronic renal failure.Cyclothymic patients with recurrent depression may require maintenance therapy for up to one year or even longer.When discontinuing treatment with TRIPRESS this should be done with a gradually reducing dosage regimen. If during this regimen there are signs of a relapse patients should be maintained on the therapy for a further 3-6 months before a second attempt at treatment discontinuation is made.
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Tripress ( Surmontil Generic Trimipramine )
Tripress (Surmontil Generic Trimipramine)
Surmontil Generic Trimipramine
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Industry News : Marquette General Health System joins Premier healthcare alliance. Marquette General Health System of Marquette, Mich., has joined the Premier healthcare alliance, consisting of more than 2,500 hospitals and 76,000 other healthcare sites, to improve care delivery.
“We believe this new partnership will help improve the value of the health services Marquette provides to our community and look forward to furthering our work with Premier.”
As a Premier owner, Marquette leverages a national purchasing network delivering industry-leading contract pricing. The not-for-profit health system formerly utilized MedAssets as its national purchasing organization.
Marquette also collaborates and compares performance with other members of the alliance to improve care efficiency while safely reducing waste and costs using the nation's largest clinical, financial and operational database.
"Premier's business model is unique in that it is completely owned by its members and thus accountable to and fully aligned with their goals," said Gary Muller, president & CEO at Marquette. "We believe this new partnership will help improve the value of the health services Marquette provides to our community and look forward to furthering our work with Premier."
The health system participates in two Premier collaboratives for additional performance improvement opportunities.
As a new member of Premier's ASCEND® (Accelerated Supply Chain Endeavor) program, Marquette aggregates, monitors and analyzes supply chain data to identify improvement opportunities. This includes simplified and consistent purchasing processes, appropriate clinical utilization and specially negotiated contracts. Members of ASCEND have saved $56 million over two years, without sacrificing the quality of care.
To support its purchasing decisions, the health system uses Premier supply chain tools like SpendAdvisor® MySpend™, to easily examine spend data.
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